منابع مشابه
Jcb_201701026 295..298
295 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 216 No. 2 295–297 https://doi.org/10.1083/jcb.201701026 Deregulated metabolism is a hallmark of cancer. Most normal differentiated cells only display low glycolysis rates, of which the resulting pyruvate is used to produce ATP through aerobic phosphorylation. In contrast, tumor cells have highly increased rates of glycolysis, after ...
متن کاملDmd049197 291..295
UDP-glucuronosyltransferases (UGTs) catalyze phase II conjugation reactions and play an important role in the inactivation and elimination of several drugs. It is well known that the UGT activity in fetal livers is low compared with the UGT activity in adult livers. In this study the mRNA expression levels of the three human subfamilies, 2B7, 2B15, and 2B17, were determined in 20 adult and 60 f...
متن کاملDc131165 295..303
Seven hundred nine (18%) patients experienced a major cardiovascular event (composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) and 706 (18%) died during a median of 5 years of follow-up. In Cox regression models, adjusting for all established risk predictors, the hazard ratio for cardiovascular events for NT-proBNPwas 1.95 per 1 SD increase (95% CI 1.72, 2.20...
متن کاملNpgrj_nsmb_1227 295..300
Notch receptors transmit signals between adjacent cells. Signaling is initiated when ligand binding induces metalloprotease cleavage of Notch within an extracellular negative regulatory region (NRR). We present here the X-ray structure of the human NOTCH2 NRR, which adopts an autoinhibited conformation. Extensive interdomain interactions within the NRR bury the metalloprotease site, showing tha...
متن کاملDynamical Outcomes of Planet–planet Scattering
Observations in the past decade have revealed extrasolar planets with a wide range of semi-major axes and eccentricities. Based on the present understanding of planet formation via core accretion and oligarchic growth, we expect that giant planets often form in closely packed configurations. While the protoplanets are embedded in a protoplanetary nebula, dissipation prevents eccentricity growth...
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ژورنال
عنوان ژورنال: Astronomische Nachrichten
سال: 1891
ISSN: 0004-6337,1521-3994
DOI: 10.1002/asna.18911282108